Predicting the Menopause

  • For many women, including the growing number who choose later-in-life pregnancy, predicting their biological clock’s relation to the timing of their menopause and infertility is critically important.A research team headed by Sowers examined the naturally occurring changes in three different biomarkers over the reproductive life of more than 600 women: follicle-stimulating hormone (FSH), anti-Mullerian hormone (AMH) and inhibin B. Researchers found that the biomarker AMH declined to a very low or non-measurable level five years prior to the final menstrual period. This decline pinpoints a critical juncture in which a woman probably has so few follicles (eggs) that her fertility becomes increasingly questionable, Sowers said. They found that the changes in AMH and inhibin B concentrations were predictive of the time to menopause.
  • A test to predict when a woman will go through the menopause has been developed by scientists who believe it will provide a ‘road map’ of fertility for older would-be mothers.The breakthrough will also help women prepare mentally for losing their fertility and allow those in their late 30s and 40s who are considering trying for a baby pinpoint just how long they have left to conceive.
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